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People with muscle diseases often struggle with progressive muscle weakness that significantly affects their mobility and quality of life. Ankle-foot orthoses are often prescribed for this, which are leg braces around the ankle. Although orthoses are available to support them, a scientific basis for choosing the right orthosis is often lacking. Niels Waterval, human movement scientist and researcher, explains: ‘Much care around orthoses is still based on experience rather than facts. Doctors and orthotists do what they think is best, but that does not always match the patient's needs.'

In patients with progressive neuromuscular disorders, the challenge lies in choosing an orthosis that provides support without restricting mobility too much. Finding the right balance between stiffness and flexibility is crucial. 'Too stiff, and it feels like wearing a ski boot. Too flexible, and the orthosis doesn't provide enough support,’ Waterval said. Moreover, the optimal orthosis varies from person to person, depending on factors such as weight, degree of muscle weakness and daily activities.  
The current approach to determining the right orthosis requires patients to try multiple models, which is time consuming and does not always lead to the best outcome. This lack of efficiency and personalization inspired Waterval's research.   

Lighter and more compact to be user-friendly for everyday situations  

Waterval has developed an innovative method to quickly adjust the stiffness of an orthosis during walking. ‘With this system, we can test different stiffnesses in one session and thus determine more quickly which support works best for a patient,’ he explains. This prototype has shown promise, but there is still work to be done. The device must become lighter and more compact to be user-friendly for everyday situations.   

The research has two main goals:  

  1. Further development of the prototype so that it meets the practical requirements of an orthosis. 
  2. Extension of testing: in addition to flat surfaces, situations such as climbing stairs, walking uphill and getting up from a chair will be considered. 'Daily life consists of more than just walking on flat terrain,' Waterval says.    

The impact of this research could not only improve the effectiveness of orthotics,  but also contribute to a scientific basis for personalized care. 'This research could be the first step towards treatment that is much more specifically tailored to individual patients and their environment,' Waterval said. 

An advanced lab with a treadmill, 3D cameras and other measuring equipment  

In the first year, the focus is on improving the orthotic device: making it lighter and smaller so that it becomes practical. 'You don't have room for large devices, because patients must also be able to put on trousers over them, for example,' explains Waterval. 
Extensive testing will follow in the second year. An important role is reserved for an advanced lab with a treadmill, 3D cameras and other measuring equipment. Here, various daily activities are simulated to see how stiffness and support affect everyday actions such as climbing stairs and standing up. All this is done with the support of a laboratory assistant and using high-end technology.  

We notice at conferences that there is a lot of enthusiasm for this approach

This research could pave the way for orthotics that seamlessly meet patient needs. Waterval hopes the results will also inspire international orthotics. 'We notice at conferences that there is a lot of enthusiasm for this approach. It's something everyone struggles with: how do you choose the right orthosis? This research can help with that,' he says. 

To give patients the freedom to live as normal a life as possible  

The research is made possible in part by the AUF Starting Scholarship. 'The stipendium is essential to realize this project. A large part goes to the development of the device and material costs,' explains Waterval. It also funds lab measurements and the presentation of results at international conferences. 
This stipendium gives Waterval the opportunity to make his vision a reality: a future where every patient receives an orthosis that perfectly matches their needs and living environment. ‘The ultimate goal is to give patients the freedom to live as normal a life as possible, despite their limitations.’